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Risk Factors of the High-Risk Pregnancy and Association with Particulate Matter

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KMID : 0892720210250010048
À¯¼öÀΠ( You Soo-In ) - Kyung Hee University College of Nursing Science

±èÁÖÈñ ( Kim Ju-Hee ) - Kyung Hee University College of Nursing Science
½ÅÇý¼÷ ( Shin Hye-Sook ) - Kyung Hee University College of Nursing Science
°­´ë·æ ( Kang Dae-Ryong ) - Yonsei University Wonju College of Medicine

Abstract

Purpose: High-risk pregnancy, resulting in major complications, such as abortion, gestational hypertension, and preterm labor, are on the rise, requiring intervention. Increased concentration of particulate matter that is 10 ¥ìg per cubic meter or less in diameter (PM10) due to increased air pollution and industrialization has recently been noted as a risk factor for health problems, and prior studies have reported that PM10 is related to abortion, gestational hypertension, and preterm labor.

Methods: This study used data from the Korean medical panel between 2008 and 2016 to identify 879 women with normal pregnancies and 301 women diagnosed with high-risk pregnancies. The association between high-risk pregnancy and PM10 was analyzed using the annual average regional concentration during the same period by the Korea Environment Corporation.

Results: At 35 years of age or older, the risk of abortion (p<0.001; 95% confidence interval [CI], 1.43?2.71) and preterm labor increased (p<0.05; 95% CI, 0.33?0.90). Married pregnant women were at a high risk of preterm labor (p<0.05; 95% CI, 0.25?0.98), and the prevalence of gestational hypertension was high in the metropolitan area (p<0.05; 95% CI, 12.09?25.93). On comparing the average annual concentration of particulate matter according to the level of atmospheric ventilation of the Korea Environment Corporation using a cutoff of ¡Â50 ¥ìg/m3, the probability of preterm labor was 2.2 times higher in groups exposed to particulate matter concentration of ¡Ã50 ¥ìg/m3 (p<0.01; 95% CI, 1.49?3.25).

Conclusion: PM10 was related to preterm labor, and the risk of preterm labor wa s high if the average annual concentration of PM10 in the individual¡¯s residential area exceeded 50 ¥ìg/m3.
KeyWords

High-risk pregnancy, Particulate matter, Risk factors
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